Design and Synthesis of a Diaza-bicyclo-naphthalen-oxiranyl-methanone Derivative. Theoretical Analysis of Their Interaction with Cytochrome P450-17A1
1. Design and Synthesis of a Diaza-bicyclo-naphthalen-oxiranyl-methanone Derivative. Theoretical Analysis of Their Interaction with Cytochrome P450-17A1

Lauro Figueroa-Valverde; Diaz Cedillo Francisco; Rosas-Nexticapa Marcela; Mateu-Armand Virginia; Montano-Tapia Elizabeth; Lopez-Ramos Maria; García-Cervera Elodia; Pool Gómez Eduardo; Hau-Heredia Lenin; Alfonso-Jimenez Alondra; Cabrera-Tuz Jhair

Volume 3, Issue 2. pp. 145-275 , March and April 2019, , Pages 194-210

http://dx.doi.org/10.22034/chemm.2018.147492.1083

Abstract
  Several agents have been used for the treatment of prostate cancer such as flutamide, galeterone, abiraterone and others; however, some of these drugs can produce some secondary effects. ...  Read More