Chemical Methodologies

Fe3O4@SiO2@Mel-Rh-Cu: A High-Performance, Green Catalyst for Efficient Xanthene Synthesis and Its Application for Magnetic Solid Phase Extraction of Diazinon Followed by Its Determination through HPLC-UV

Sahar Peiman; Behrooz Maleki; Milad Ghani

Volume 8, Issue 4 , April 2024, , Pages 257-278

https://doi.org/10.48309/chemm.2024.442693.1767

Abstract

A novel, high-performance, recyclable heterogeneous catalyst functionalized with melamine was advantageously prepared and rhodanine on magnetic silica was successfully carried out. ... Read More A novel, high-performance, recyclable heterogeneous catalyst functionalized with melamine was advantageously prepared and rhodanine on magnetic silica was successfully carried out. After that, the Cu ions were coordinated with the existing ligands decorated on the magnetic silica surface. This catalyst was identified by different analyses and acted as a recoverable catalyst for xanthene synthesis. Its advantages include the solvent-free conditions of the reaction, the high efficiency of the products in a short period of time, as well as its simple collection from the reaction environment. Moreover, the prepared sorbent has been developed for the extraction of diazinon from different real samples through magnetic solid phase extraction (MSPE). Under optimal conditions, the linear range for measuring diazinon was 0.5-200 µg L-1. The coefficient of determination (R2) was 0.9985. The limit of detection (LOD) of the method was 0.08 μg L-1. Relative standard deviation values (RSD%) for the concentration of 10.0 μg L-1 and 100 μg L-1 were between 5.3% and 5.9%. Finally, the proposed method was used to determine diazinon in orange and agricultural water. The results showed that the percentage of relative recovery of the selected toxin in the studied real samples was between 92 and 105.Moreover, the prepared sorbent has been developed for the extraction of diazinon from different real samples through magnetic solid phase extraction (MSPE). The parameters affecting the extraction were optimized by response surface methodology (RSM). The optimal extraction conditions were 15 min for contact time, 7 mg for sorbent amount, and 0% (w/v) for NaCl concentration.Moreover, 20 µL of methanol was used to elute the extracted analyte. Under optimal conditions, the linear range for measuring diazinon was 0.5-200 µg L-1. The coefficient of determination (R2) was 0.9985. The limit of detection (LOD) of the method was 0.08 μg L-1. Relative standard deviation values (RSD%) for the concentration of 10.0 μg L-1 and 100 μg L-1 were between 5.3% and 5.9%. Finally, the proposed method was used to determine diazinon in orange and agricultural water. The results showed that the percentage of relative recovery of the selected toxin in the studied real samples was between 92 and 105.

Phytochemical Evaluation of Aerial Parts of Eryngium Billardieri growing in Iran

Keyvan Sardari; Abbas Delazar; Hadi Ghanbari; Solmaz Asnaashari; Parina Asgharian

Volume 8, Issue 1 , January 2024, , Pages 47-57

https://doi.org/10.48309/chemm.2024.427947.1740

Abstract

Introduction: Eryngium plants represent the most diverse species within the Apiaceae family, with approximately 250 species. Numerous species of Eryngium, including Eryngium campestre ... Read More Introduction: Eryngium plants represent the most diverse species within the Apiaceae family, with approximately 250 species. Numerous species of Eryngium, including Eryngium campestre and E. foetidum, have been used for centuries in traditional medicine. E. billardieri was selected for this study due to its purported applications in traditional Iranian medicine, as well as the absence of prior research on the chemical constituents within this plant.Materials and methods: The aerial parts of the plant were extracted by n-hexane, dichloromethane, and methanol (MeOH) by a Soxhlet apparatus. The MeOH extract was exposed to C18 Sep-Pak fractionation cartridge by a step gradient of MeOH-H2O. Further purification was performed by preparative HPLC and the purified compounds were separated to be elucidated with H NMR and C NMR results. The essential oil was obtained by the Clevenger apparatus. The n-hexane extract was transformed into methyl ester through a process involving saponification and esterification and the obtained essential oil and fatty acids were analyzed using a flame ionization detector (FID) and a DB-1 capillary column.Results: The 40% methanol extract led to the identification of two compounds such as decursine and Chlorogenic acid. The essential oil composition analysis yielded the following results: approximately 92% of the essential oil compounds were identified. The predominant compounds were isofenchol (36.85%), germacrene D (7.69%) and gurjunene (6.67%). The analysis of methyl esters revealed the presence of four fatty acid compounds: oleic acid with 27.2%, elaidic acid with 6.91%, palmitic acid with 4.62%, and stearic acid with 2.55% of the total area.Conclusion: Two substances (decursine and chlorogenic acid) were isolated from the methanol extract, and oleic acid was isolated and identified from the n-hexane extract. Concerning the phytochemical potential inherent in this genus and specifically in this plant, further extensive research in this domain is warranted.

Comparison of Different Extracts of Nettle in Quercetin and Evaluation of its Antimicrobial Activity

Mahsa Taghvaei; MohamMad Fazilati; Habibollah Nazem; Saeed Habibollahi; Faegh Bastani

Volume 4, Issue 5 , September and October 2020, , Pages 572-583

https://doi.org/10.22034/chemm.2020.107198

Abstract

Nettle (Urtica dioica L.) is one of the most well-known medicinal plants. It has been mostly used for medical purposes. This study summarizes extensive results on the antimicrobial ... Read More

Quantification of A β Adrenergic Receptor Drug Mirabegron by Stability Indicating LC Method and Uv–visible Spectroscopic Method in Bulk and Pharmaceutical Dosage Form

Preeti N. Yadav; Usmangani K. Chhalotiya; Kesha M. Patel; Jinal N. Tandel

Volume 4, Issue 3 , May and June 2020, , Pages 340-358

https://doi.org/10.33945/SAMI/CHEMM/2020.3.11

Abstract

In this work, an accurate, sensitive, reproducible and precise stability indicating high performance liquid chromatographic (HPLC) method and ultra violet (UV)-visible spectroscopic ... Read More

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Keywords = HPLC

Fe3O4@SiO2@Mel-Rh-Cu: A High-Performance, Green Catalyst for Efficient Xanthene Synthesis and Its Application for Magnetic Solid Phase Extraction of Diazinon Followed by Its Determination through HPLC-UV

Abstract

Phytochemical Evaluation of Aerial Parts of Eryngium Billardieri growing in Iran

Abstract

Comparison of Different Extracts of Nettle in Quercetin and Evaluation of its Antimicrobial Activity

Abstract

Quantification of A β Adrenergic Receptor Drug Mirabegron by Stability Indicating LC Method and Uv–visible Spectroscopic Method in Bulk and Pharmaceutical Dosage Form

Abstract