Furat A. Hiawi; Inaam H. Ali
Abstract
The interaction between foods additives and drugs can influence the effectiveness of drug therapy, and also on the adverse reactions assessments of numerous drugs. Food colorants dyes ...
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The interaction between foods additives and drugs can influence the effectiveness of drug therapy, and also on the adverse reactions assessments of numerous drugs. Food colorants dyes are chemical compounds which have been added to various types of foods. In this work, the colorant food dye indigo carmine (IC), as adsorbate, and loratadine drug, as adsorbent, was studied through the adsorption interaction behavior. The adsorption process was carried out at various concentrations of dyes, various dosages of drug, and different temperature (288-318K). The Langmuir and Freundlich adsorption isotherm were used to explain the equilibrium data, with Freundlich giving the best fit to the data. The adsorption kinetics follows pseudo-second order kinetics and the adsorption process were spontaneous, exothermic, and negative value of entropy demonstrates reductions in the disorder at the solid-solution interface after IC adsorption on loratadine.
