Iron (III) Phosphate-Catalyzed Condensation Reaction of Amines with Cyclohexyl Isocyanate and Aldehydes user Environmentally condition
Farahnaz
K. Behbahani
Department of Chemistry, Karaj Branch, Islamic Azad University, Karaj, Iran.
author
Raheleh
Shahbazi
Department of Chemistry, Karaj Branch, Islamic Azad University, Karaj, Iran.
author
text
article
2018
eng
Synthesized DCU analogous such as benzoyl-N,N’-dicyclo hexyl urea, N,N’-dicyclohexyl-N-3,5-dinitro benzoyl urea and N,N’-dicyclohexyl-N-[(E)-3-phenylacryloyl]urea were found to possess free radical scavenging activity. Benzotriazepines comprise an interesting class heteroaromatic compounds because of their significant biological and pharmaceutical properties such as antibacterial, antiviral, psychotropic and antimalarial properties. In this paper, synthesis of 4-aryl-3-cyclohexyl-4,5-dihydro-1H-benzo[f][1,3,5] triazepin-2(3H)-one and N'',N''''''-1,2-phenylenebis N-cyclohexylurea is reported by condensation reaction of amines with cyclohexylisocyanate and aldehydes using iron (III) phosphate as catalyst under environmentally conditions. Melting points, IR spectra 1HNMR spectra were obtained. Analytical TLC of all reactions was performed on Merck precoated plates (silica gel 60 F-254 on aluminum). GC/Mass spectra were recorded on an Agilent 6890 GC Hp-5 capilary 30m × 530µm × 1.5 µm nominal operating at 70 eV.
Chemical Methodologies
Sami Publishing Company
2645-7776
2
v.
4
no.
2018
270
276
https://www.chemmethod.com/article_63503_a7363cec0d8990f13b749f63e6e0516c.pdf
dx.doi.org/10.22034/chemm.2018.63503
Effective SWCNTs/Nafion Electrochemical Sensor for Detection of Dicapthon Pesticide in Water and Agricultural Food Samples
Puthalapattu
Prasad
Electroanalytical Lab, Department of Chemistry, Sri Venkateswara University, Tirupati-517502, A.P., India.
author
Aruna
P
Electroanalytical Lab, Department of Chemistry, Sri Venkateswara University, Tirupati-517502, A.P., India.
author
Prabhakar
K
Department of Chemistry, D.K.W Govt. Degree College, Nellore, A.P., India.
author
N.Y.
Sreedhar
Electroanalytical Lab, Department of Chemistry, Sri Venkateswara University, Tirupati-517502, A.P., India.
author
text
article
2018
eng
In this study, we report an effective electrochemical sensor of single-walled carbon nanotubes (SWCNTs)/Nafion glassy carbon electrode (SWCNTs/Nafion/GCE) for determination of dicapthon in water and agricultural food samples. The electroanalytical performance of SWCNTs/Nafion/GCE toward the reduction of dicapthon was analyzed via cyclic and differential pulse voltammetry. The optimum parameters like the effect of pH, concentration of dicapthon solution, scan rate, accumulation potential and accumulation time were thoroughly optimized. At electrochemical optimum conditions, voltammetric reduction peak exhibited a linear with the concentration of dicapthon from 0.2‒60.0 μgmL−1, with a detection limit of 0.036 μgmL−1. The modified electrochemical sensor showed good stability and reproducibility. The determination of dicapthon was examined with SWCNTs/Nafion/GCE in water and agricultural food samples.
Chemical Methodologies
Sami Publishing Company
2645-7776
2
v.
4
no.
2018
277
290
https://www.chemmethod.com/article_63835_ff8ba328fc7b0d2f556831d9b823191a.pdf
dx.doi.org/10.22034/chemm.2018.63835
Semi-empirical Estimation of Rhodamine 6G’s Fluorescence Lifetimes from Fluorescence Quenching Data
Abimbola
Ogunsipe
Department of Chemistry, Federal University of Petroleum Resources, Effurun, Nigeria
author
text
article
2018
eng
The fluorescence quenching of rhodamine 6G by hydroquinone in methanol, water and dimethylsulphoxide (DMSO) is explored. A combination of solvent parameter could be necessary to explain solvatochromism in rhodamine 6G as the consideration for solvent refractive index alone is insufficient. Stokes’ shifts ranged between 25 and 29 nm. Rhodamine 6G’s fluorescence was effectively quenched by hydroquinone within the quencher’s concentration (0.01 to 0.05 M) which was used in this work, and the quenching data were in conformity with the Stern-Volmer’s model. Stern-Volmer’s constants (KSV) were 47.1, 29.6 and 14.8 M-1 in methanol, water and DMSO respectively. These values, together with the calculated bimolecular rate constants (kD) in the respective solvents, were used in the semi-empirical estimation of the fluorescence lifetimes (tF) of rhodamine 6G in the individual solvents. The tF determined values (3.78, 3.89 and 4.36 ns in methanol, water and DMSO respectively) are comparable with literature values.
Chemical Methodologies
Sami Publishing Company
2645-7776
2
v.
4
no.
2018
291
298
https://www.chemmethod.com/article_65399_eafae563ea0211652e167074f7acd388.pdf
dx.doi.org/10.22034/chemm.2018.65399
Experimental Determination of Nutrient release from Neem Oil (Azadirachta indica) coated urea
Shiv
Meena
Department of Chemical Engineering, Malaviya National Institute of Technology, Jaipur-302017
author
Manish
Vashishtha
Department of Chemical Engineering
Malaviya National Institute of Technology, Jaipur-302017 (INDIA)
author
Ankush
Meena
Department of Chemical Engineering, Malaviya National Institute of Technology, Jaipur-302017
author
text
article
2018
eng
An accurate estimate of nutrient release pattern from controlled release fertilizer (CRF) is required both for manufactures as well for farmers because it helps them in understanding fertilizer potency and nutrient planning for the crops. Understanding the release pattern of different types of CRF under laboratory conditions as well as in the crop-field is essential in order to determine the fertilizer utilization efficiency on plant growth. The present work explains a simple experimental approach to understand the nutrient release from Neem coated urea (NCU). The coating of Urea with Neem oil (derived from seeds and leaves) inhibit the process of nitrification and reduce formation of nitrates which in-turn will reduce N2O emissions. It prevents the loss of urea in the soil. It also controls a large number of pests such as caterpillars, beetles, leafhoppers, borer, mites etc. Also Neem coating is biodegradable and so it is environment friendly as compared to many non biodegradable polymers used as coating materials in CRF.UV-Vis spectrometer is employed to determine the amount of nitrogen released. The approach reduced analytical error by preventing sample dilution before measuring. According to laboratory results obtained UV-Vis spectrometer proved to be a handy and efficient equipment for studying the nutrient release behavior from CRF. The release profile presents a sigmoidal shape which is in good agreement from the other works in the area reported in the literature. The experimental results obtained are also in tune with the criteria specified by European Committee for Standardization for CRF.
Chemical Methodologies
Sami Publishing Company
2645-7776
2
v.
4
no.
2018
299
307
https://www.chemmethod.com/article_66186_c3168fb2679a5a165af4e57c539b06e1.pdf
dx.doi.org/10.22034/chemm.2018.66186
Measurement and Calculation of Physico-chemical Properties of Binary Mixtures Containing Xylene and 1-Alkanol
Mohammad
Almasi
Department of Applied Chemistry, Faculty of Science, Malayer University, Malayer, 65174, Iran.
author
text
article
2018
eng
Measured densities and viscosities of xylene, 1-butanol, 1-pentanol, 1-hexanol, 1-heptanol and 1-octanol and their binary mixtures with xylene in the liquid state were reported over the whole composition range at 298.15 K and atmospheric pressure. From the experimental data, excess molar volumes and deviations in viscosity were calculated and interpreted in terms of intermolecular interactions and structural effects. Statistical association fluid theory (SAFT) and perturbed chain statistical association fluid theory (PC-SAFT) were applied to correlate the densities of binary mixtures. These models can predict the density accurately but obtained values by the PC-SAFT are closely matched with the experimental data.
Chemical Methodologies
Sami Publishing Company
2645-7776
2
v.
4
no.
2018
308
314
https://www.chemmethod.com/article_65188_8baf57c0d7034dbf6f45ca730e3db640.pdf
dx.doi.org/10.22034/chemm.2018.65188
A Simple and Sensitive Method for the Ultra Trace Determination of Potential Genotoxic Impurities in Abacavir Sulfate by LC-MS
Mohit
Jain
Micro Labs Ltd., API R&D Centre, Bommasandra Jigani Link Road, KIADB INDL Area, Bommasandra, Bangalore-560105, Karnataka, India.
author
Saroj Kumar
Paul
Micro Labs Ltd., API R&D Centre, Bommasandra Jigani Link Road, KIADB INDL Area, Bommasandra, Bangalore-560105, Karnataka, India.
author
Madhava Rao
Mannam
Micro Labs Ltd., API R&D Centre, Bommasandra Jigani Link Road, KIADB INDL Area, Bommasandra, Bangalore-560105, Karnataka, India.
author
Sujeet
Shrivastava
Micro Labs Ltd., API R&D Centre, Bommasandra Jigani Link Road, KIADB INDL Area, Bommasandra, Bangalore-560105, Karnataka, India.
author
Hiriyanna
S.G.
Micro Labs Ltd., API R&D Centre, Bommasandra Jigani Link Road, KIADB INDL Area, Bommasandra, Bangalore-560105, Karnataka, India.
author
Pramod
Kumar
Micro Labs Ltd., API R&D Centre, Bommasandra Jigani Link Road, KIADB INDL Area, Bommasandra, Bangalore-560105, Karnataka, India.
author
text
article
2018
eng
A new LC-MS based method was developed to detect three potential genotoxic impurities namely, N',N'''-(4,6-dichloropyrimidine-2,5-diyl)bis[N,N-dimethyl(imidoformamide)]} (Impurity-I), {N-(2-amino-4-chloro-6-{[(1S,2R)-2-(hydroxymethyl)cyclopent-3-en-1-yl]amino}pyrimidin-5-yl)formamide} (Impurity-II) and {(1R,5S)-5-[(2,5-diamino-6-chloropyrimidin-4-yl)amino]cyclopent-2-en-1-yl}methanol (Impurity-III), at low level in Abacavir sulfate, a nucleoside reverse transcriptase inhibitor. It utilizes Zorbax phenyl hexyl column (150 mm x 4.6 mm, 3.5 μm) with electrospray ionization in selected ion monitoring (SIM) mode for quantitation of these PGIs. The method is able to quantify Impurity-I at 0.74 ppm, Impurity-II and Impurity-III at 0.73 ppm with respect to 5.0 mg/mL of Abacavir sulfate. The method was found to be linear in the range of LOQ to 150% of Toxicological Threshold Concentration level of 2.5 ppm. The correlation coefficients of PGI’s obtained were >0.999 in each case. The method accuracy of these PGI’s is in the range between 88.7-115.0%. The method is sensitive, specific, linear, accurate, precise and meets the criteria of validation as per International Conference on Harmonization.
Chemical Methodologies
Sami Publishing Company
2645-7776
2
v.
4
no.
2018
315
323
https://www.chemmethod.com/article_66185_675e4caa5ea8a111da192bebfb296e7d.pdf
dx.doi.org/10.22034/chemm.2018.66185
Prediction of Atmospheric Corrosion of Ancient Door Knockers via Neural Networks
Shahrzad
Houshmandynia
Department of MBA - Marketing Islamic Azad University-Arak Branch, P.O. Box 1997683953, Arak, Iran
author
Roya
Raked
Department of masters of Handicrafts, Art and Architecture of Ardakan, Yazd, Iran
author
Fardad
Golbabaei
Department of Wood and Paper Science, Research Institute of Forests and Rangelands, Agricultural Research, Education and Extension Organization (AREEO), Tehran, Iran
author
text
article
2018
eng
The importance of door knockers persuades us to anticipate the atmospheric corrosion through Neural Network (NN) which is validated by data originated from literature. NNs are used in order to anticipate the effective parameter on bronze atmospheric corrosion including the ambient temperature, exposition time, relative humidity, PH, SO2 concentration as an air pollutant and also metal’s precipitations. As these factors are extremely complicated, exact mathematical language of the diverse metals corrosion are not comprehended. The results of this study showed that SO2 concentration as an air pollutant and time of exposition are the fundamental effects on corrosion weight loss of bronze.
Chemical Methodologies
Sami Publishing Company
2645-7776
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v.
4
no.
2018
324
332
https://www.chemmethod.com/article_65388_af4954e84a4f79e2adf665952a32978e.pdf
dx.doi.org/10.22034/chemm.2018.65388
Efficient Synthesis of β-Lactam-Containing α-Aminophosphonates Using Fumaric Acid as Mild Catalyst
Vijaya Bhaskar
Vangala
Department of Chemistry, Eurofins Advinus Ltd., 21 & 22, Phase II, Peenya Industrial Area, Bengaluru-560058, Karnataka, India
author
Hari
Pati
Department of Chemistry, Eurofins Advinus Ltd., 21 & 22, Phase II, Peenya Industrial Area, Bengaluru-560058, Karnataka, India
author
text
article
2018
eng
A short and efficient protocol for the synthesis of novel α-aminophosphonate esters containing β-lactam moiety is described. Inexpensive and mild catalyst such as fumaric acid was used for the synthesis of α-aminophosphonate esters by reacting N-(4-methoxyphenyl)-2-(substituted) propiolactam-3-carbaldehyde with amine and triethylphosphite in acetonitrile at reflux. α-aminophosphonate esters containing β-lactam hybrids were obtained in good yield and purity.A short and efficient protocol for the synthesis of novel α-aminophosphonate esters containing β-lactam moiety is described. Inexpensive and mild catalyst such as fumaric acid was used for the synthesis of α-aminophosphonate esters by reacting N-(4-methoxyphenyl)-2-(substituted) propiolactam-3-carbaldehyde with amine and triethylphosphite in acetonitrile at reflux. α-aminophosphonate esters containing β-lactam hybrids were obtained in good yield and purity.
Chemical Methodologies
Sami Publishing Company
2645-7776
2
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4
no.
2018
333
340
https://www.chemmethod.com/article_66128_d18fe72bb4b0fdcc7f9b5cdaa64d5472.pdf
dx.doi.org/10.22034/chemm.2018.66128