@article { author = {Narran, Shetha Fadhil and Mohammed, Suad Salman and Omer, Maab Khattab and Hussein, Iftikhar Ahmed and Jawad, Noor Mohammed and Shweish, Batool Karim}, title = {Synthesis and Biological Activities of Some New Derivatives Based on 5-Styryl-2-amino-1,3,4-thiadiazole}, journal = {Chemical Methodologies}, volume = {6}, number = {2}, pages = {83-90}, year = {2022}, publisher = {Sami Publishing Company}, issn = {2645-7776}, eissn = {2588-4344}, doi = {10.22034/chemm.2022.2.1}, abstract = {In this research, 5-Styryli-2-amino-1, 3, 4-thiadiazole [C1] was prepared from the reaction of acid 3-phenyl propenoic acid with thiosemicarbazide. Amic acids [C2-C5] were synthesized by reactive compound [C1] with different types of hydrides, then [C2, C4] were treated with AC2O in the presence of NaOAC as a catalyst giving Imide compounds [C6, C7]. The structure of the new derivatives was confirmed via FT-IR spectroscopy, some of which were confirmed via 1H-NMR spectroscopy. Three of these new derivatives were evaluated by their Esherichiacoli, Staphylococcus, and Rhizopus emporium.}, keywords = {1,3,4-Thiadiazle,Amic acid,Imide,anti-bacterial,Anti-fungal}, url = {https://www.chemmethod.com/article_140134.html}, eprint = {https://www.chemmethod.com/article_140134_0c6c5b6943001cfb0c119d33236de0ac.pdf} }