%0 Journal Article %T Efficient Synthesis of β-Lactam-Containing α-Aminophosphonates Using Fumaric Acid as Mild Catalyst %J Chemical Methodologies %I Sami Publishing Company %Z 2645-7776 %A Vangala, Vijaya Bhaskar %A Pati, Hari %D 2018 %\ 10/01/2018 %V 2 %N 4 %P 333-340 %! Efficient Synthesis of β-Lactam-Containing α-Aminophosphonates Using Fumaric Acid as Mild Catalyst %K Fumaric acid %K α-aminophosphonate ester %K β-Lactam %R 10.22034/chemm.2018.66128 %X A short and efficient protocol for the synthesis of novel α-aminophosphonate esters containing β-lactam moiety is described. Inexpensive and mild catalyst such as fumaric acid was used for the synthesis of α-aminophosphonate esters by reacting N-(4-methoxyphenyl)-2-(substituted) propiolactam-3-carbaldehyde with amine and triethylphosphite in acetonitrile at reflux. α-aminophosphonate esters containing β-lactam hybrids were obtained in good yield and purity.A short and efficient protocol for the synthesis of novel α-aminophosphonate esters containing β-lactam moiety is described. Inexpensive and mild catalyst such as fumaric acid was used for the synthesis of α-aminophosphonate esters by reacting N-(4-methoxyphenyl)-2-(substituted) propiolactam-3-carbaldehyde with amine and triethylphosphite in acetonitrile at reflux. α-aminophosphonate esters containing β-lactam hybrids were obtained in good yield and purity. %U https://www.chemmethod.com/article_66128_d18fe72bb4b0fdcc7f9b5cdaa64d5472.pdf