TY - JOUR ID - 147794 TI - Synthesis and Characterization of Heterocyclic Compounds Derived from 2-Mercaptobenzothiozole and Study of Their Biological Activities JO - Chemical Methodologies JA - CHEMM LA - en SN - 2645-7776 AU - Hamad, Bushra Karim AU - Ahamed, Mohmmad R. AD - Department of Chemistry, College of Science, University of Baghdad, Baghdad, Iraq Y1 - 2022 PY - 2022 VL - 6 IS - 5 SP - 409 EP - 417 KW - Schiff base KW - حhenyl isothiocyanate KW - یiazetidine DO - 10.22034/chemm.2022.332101.1447 N2 - In this study, Schiff base derivatives were reacted with phenyl isothiocyanate and chloroacetic acid to give diazetidine-2-thione and oxazolidinone derivatives. The Schiff base derivatives containing the 2-mercabto benzothiazole moiety were obtained via reaction of a different aromatic aldehyde with 2-(benzothiazol-2-ylthio) acetohydrazide. Furthermore, 2-(benzothiazol-2-ylthio) acetohydrazide were obtained via reaction of 2-mercabto benzothiazole with ethyl chloroacetate, then with hydrazine hydrate. The newly synthesized compounds were characterized via spectral data (FT-IR and 1H-NMR). The antibacterial activity was studied against examples of Gram-positive and Gram-negative bacteria. UR - https://www.chemmethod.com/article_147794.html L1 - https://www.chemmethod.com/article_147794_d908472a93bb65a58b6843b96047d87e.pdf ER -