TY - JOUR ID - 156809 TI - Synthesis and Characterization of New Thiazolidinone and Oxazolidinone Heterocyclic Derivatives from 2-Marcapto-1,3,4-Thiadiazole Compounds JO - Chemical Methodologies JA - CHEMM LA - en SN - 2645-7776 AU - S. Salman, Bashar AU - R. Ahmed, Mohammed AD - Department of Chemistry, College of Science, Baghdad University, Baghdad, Iraq Y1 - 2022 PY - 2022 VL - 6 IS - 12 SP - 997 EP - 1006 KW - Heterocyclic compounds Thiadiazole 5-Aryle KW - 1 KW - 3 KW - 4-thiadiazole Schiff base Oxazolidinone Thiazolidinone DO - 10.22034/chemm.2022.357813.1601 N2 - The previous effort involved the synthesis of unprecedented Schiff's bases compounds of hydrazine hydrate linked with ethyl 4-hydroxybenzoate, which in turn reacted with carbon disulfide (CS2) and potassium hydroxide (KOH) as catalyst to synthesize 2-marcapto-1,3,4-thiadiazole which reacts with methyl bromoacetate in the presence of triethyl amine N(CH2CH3)3 to form an ester whose methoxy group is converted into a hydrazide, and then reacts with different aromatic aldehydes to form Schiff bases, from which the thiazolidinone and oxazolidinonefive-membered ring heterocyclic compounds' derivatives were formed. All synthetic substances have high yields. The melting points of all compounds and some of their 1H-NMR and FT-IR spectra, were used to authenticate their identities. UR - https://www.chemmethod.com/article_156809.html L1 - https://www.chemmethod.com/article_156809_ddf417097da69ef8be386f45f24662e3.pdf ER -