TY - JOUR ID - 83972 TI - N1,N1,N2,N2-Tetramethylethylenediaminium-N1,N2-disulfonic Acid Trifluoroacetate as Highly Effectual and Dual-Functional Catalyst for the Reaction of β-Ketoesters with Aryl Aldehydes and Urea/Thiourea JO - Chemical Methodologies JA - CHEMM LA - en SN - 2645-7776 AU - Karami, Mostafa AU - Gholami, Bentolhoda AU - Hekmat-Zadeh, Tahereh AU - Zare, Abdolkarim AD - Department of Chemistry, Payame Noor University, PO Box 19395-3697 Tehran, Iran Y1 - 2019 PY - 2019 VL - 3 IS - 4 SP - 509 EP - 518 KW - 3,4-dihydropyrimidin-2-(1H)-one KW - 3,4-dihydropyrimidin-2-(1H)-thione KW - Ionic Liquid KW - Dual-functional catalyst N1,N1,N2,N2-Tetramethylethylenediaminium-N1,N2-disulfonic acid trifluoroacetate ([TMEDSA][TFA]2) DO - 10.22034/chemm.2019.157916.1111 N2 - In this research, the one-pot multi-component reaction of β-ketoesters with aryl aldehydes and urea/thiourea has been performed using a dual-functional ionic liquid-catalyst namely N1,N1,N2,N2-tetramethylethylenediaminium-N1,N2-disulfonic acid trifluoroacetate ([TMEDSA][TFA]2) in solvent-free conditions. By reason of dual-functionality of the catalyst (possessing acidic and basic sites), and also having two numbers of each site, it was highly effectual and general catalyst, and afforded the products {3,4-dihydropyrimidin-2-(1H)-ones and 3,4-dihydropyrimidin-2-(1H)-thiones} in short times with excellent yields. Moreover, a plausible mechanism based on dual-functionality of the catalyst has been proposed. UR - https://www.chemmethod.com/article_83972.html L1 - https://www.chemmethod.com/article_83972_3637cda0af7e85cc011e9773e6a672f0.pdf ER -