%0 Journal Article %T Four-Component Synthesis of Polyhydroquinolines via Unsymmetrical Hantzsch Reaction Employing Cu-IRMOF-3 as a Robust Heterogeneous Catalyst %J Chemical Methodologies %I Sami Publishing Company %Z 2645-7776 %A Taghavi, Reza %A Rostamnia, Sadegh %D 2022 %\ 09/01/2022 %V 6 %N 9 %P 639-648 %! Four-Component Synthesis of Polyhydroquinolines via Unsymmetrical Hantzsch Reaction Employing Cu-IRMOF-3 as a Robust Heterogeneous Catalyst %K Metal-organic Frameworks %K Polyhydroquinoline, IRMOF-3, Unsymmetrical Hantzsch reaction %R 10.22034/chemm.2022.340599.1511 %X In this report, an IRMOF-3 was synthesized via a solvothermal method and then used as support for stabilizing Cu(II) ions. Characterization methods such as FT-IR, XRD, SEM, and BET were employed to analyze produced Cu@IRMOF-3, demonstrating that the suggested catalyst effectively conserved its structure throughout the synthesis processes. The FT-IR results indicate that the presence of the -NH2 group in the structure of the MOF helped stabilize the Cu(II) ions. The manufactured catalyst was used to prepare polyhydroquinoline derivatives which showed superior results. %U https://www.chemmethod.com/article_151361_497ec68336fe6b899ece540616665a1a.pdf