Chemical Methodologies

Original Article

A Molecular Docking Study: Benzoxazolone Derivatives against SARS-CoV-2 Omicron Subvariant EG.5.1

Emine Erdag

Volume 7, Issue 11 , November 2023, Pages 825-836

https://doi.org/10.48309/chemm.2023.423231.1736

Abstract

In the ongoing COVID-19 pandemic, it is important to develop treatment strategies and new drug candidates that target the interactions between the receptor-binding domains (RBDs) of ... Read More

Original Article

Radiochemical Separation Relevant to the no-carrier-added Production of 90Nb: A Potential Radiopharmaceutical for PET Imaging

Houshyar Seyedi; Amir Nikjou; Alireza Goosheh; Parvin Sarabadani; Mahdi Sadeghi

Volume 7, Issue 11 , November 2023, Pages 837-852

https://doi.org/10.48309/chemm.2023.416689.1721

Abstract

Niobium-90 (90Nb), a radioisotope of paramount importance in the field of nuclear medicine, has been effectively synthesized and separated from target materials through natZr(p,n)90Nb ... Read More

Original Article

Evaluation of Several Austenitic Types of Stainless Steel's Chemical Corrosion Resistance

Hala. M. Hassan

Volume 7, Issue 11 , November 2023, Pages 853-870

https://doi.org/10.48309/chemm.2023.421394.1730

Abstract

This study aims to evaluate the efficacy of compounds as corrosion inhibitors for stainless steel in hydrochloric acid solution using gravimetric technique and electrochemical measurements. ... Read More

Original Article

Studying the Structural and Optical Properties of Thin Compound Oxide Films Based on TiO2: NiO: In2O3 Nanostructure

Fuad .T Ibrahim; M. Abd Shahoodh; S. Guermazi

Volume 7, Issue 11 , November 2023, Pages 871-882

https://doi.org/10.48309/chemm.2023.409731.1693

Abstract

Spray pyrolysis has been used to fabricate different mixed TiO2/NiO/In2O3 nanostructures. TiO2/NiO/In2O3 has been structurally and optically explored using X-ray diffraction, field ... Read More

Original Article

Molecular Docking and Dynamics Analysis of COVID-19 Main Protease Interactions with Alkaloids from Hyoscyamus Niger and Datura Stramonium

Neda Tadayon; Ali Ramazani

Volume 7, Issue 11 , November 2023, Pages 883-903

https://doi.org/10.48309/chemm.2023.422059.1732

Abstract

SARS-CoV-2 is the largest pandemic in the modern world and the etiological agent of COVID-19. Up to now, many efforts have been made to achieve the right drugs and vaccines against ... Read More SARS-CoV-2 is the largest pandemic in the modern world and the etiological agent of COVID-19. Up to now, many efforts have been made to achieve the right drugs and vaccines against the new Coronavirus. Virtual screening methods are highly effective because they are cost-effective and efficient, making them widely utilized in the development of new herbal medicines. This research utilized molecular docking and dynamics studies to identify potential compounds derived from the plants Hyoscyamus niger and Datura stramonium. Alkaloids, a significant group of fundamental compounds found in herbal medicines, have garnered substantial attention due to their diverse pharmacological and medicinal properties. A comprehensive examination of 73 alkaloid molecules was undertaken due to their potential therapeutic properties, encompassing anti-inflammatory, antioxidant, anti-asthma, anti-viral, anti-microbial, and anti-cancer effects. This was based on the notion that these compounds could potentially be effective in treating the new coronavirus. Thus, out of seventy-three compounds five (Hyoscyamine, Moupinamide, Littorina, 7-Hydroxyhyoscyamine, 3-tigloyloxy-6-isobutyryloxy-7-hydroxytropane) with the lowest binding energies (-7, -6.8, -6.4, -6.2, and -6.1Kcal/mol, respectively) were selected for docking study. In addition, atomistic molecular dynamics simulations were conducted to investigate the dynamic behaviour of Mpro: ligand complexes. The alkaloid moupinamide showed promising activity in inhibiting the main protease (Mpro). The ability of the alkaloid moupinamide to obstruct the primary protease (Mpro) of the novel coronavirus has to be confirmed by additional investigation. Studies conducted in vivo, in vitro, and in clinical trials are necessary to support this assertion.Datura stramonium and Hyoscyamus niger, are medicinal plants that belong to the Solanaceae family. Alkaloids are part of the chemical defense in plants that contain low molecular weight nitrogen. Coronavirus disease (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus. Molecular docking is used to predict how a protein will fit with small molecules. Molecular dynamics simulations show how each atom in a protein or other molecular system moves over time.

Green Chemistry: Principles, Applications, and Disadvantages

Wanisa Abdussalam-Mohammed; Amna Qasem Ali; Asma O. Errayes

Volume 4, Issue 4 , July and August 2020, , Pages 408-423

https://doi.org/10.33945/SAMI/CHEMM.2020.4.4

Abstract

This work provides an overview on applicability of 12 principles of green chemistry. Green chemistry is a term that indicates the creation of chemical products and procedures that reduces ... Read More

Cu Nanoparticle: Synthesis, Characterization and Application

N.S. Powar; V. J. Patel; P.K. Pagare; R.S. Pandav

Volume 3, Issue 4 , July and August 2019, , Pages 457-480

https://doi.org/10.22034/chemm.2019.154075.1112

Abstract

The applications of copper nanoparticle are gradually increased because of Cu is inexpensiveness and high abundance in nature. However, synthesis of copper nanoparticles is very challenging ... Read More

Preparation of Xanthan Magnetic Biocompatible Nano-Composite for Removal of Ni^2+ from Aqueous Solution

Alireza Bozorgian; Soroush Zarinabadi; Amir Samimi

Volume 4, Issue 4 , July and August 2020, , Pages 477-493

https://doi.org/10.33945/SAMI/CHEMM.2020.4.9

Abstract

This study investigates the uptake of the nickel (II) metal ions from aqueous sources using the xanthan magnetic biocompatible nano-composites. The desired nano-sorbent was first synthesized, ... Read More

Water Purification Using Nanotechnology an Emerging Opportunities

Shalini Chaturvedi; Pragnesh N. Dave

Volume 3, Issue 1 , January 2019, , Pages 115-144

https://doi.org/10.22034/chemm.2018.143461.1069

Abstract

The most important component for living beings on the earth is access to clean and safe drinking water. Globally, water scarcity is pervasive even in water rich areas as immense pressure ... Read More

Improved Photostabilization of Chlorpyrifos Insecticide with Novel Benzil Derivatives

Gautam M. Patel; Hemant S. Parmar; Pradeep T. Deota

Volume 3, Issue 4 , July and August 2019, , Pages 481-493

https://doi.org/10.22034/chemm.2018.151723.1101

Abstract

Chlorpyrifos, an organophosphorus insecticide, is widely used in agricultural and non-agricultural areas all over the world. During field application, it readily undergoes degradation ... Read More

Original Article

Investigation of Some Phenolic Compounds as iNOS Inhibitors: An in silico Approach

Emine Erdag

Articles in Press, Accepted Manuscript, Available Online from 19 November 2023

https://doi.org/10.48309/chemm.2023.424609.1738

Abstract

Nitric oxide synthase (NOS) preferentially produces its inducible isoform (iNOS) in several cells, including macrophages, which are in charge of the immunological response. It is widely ... Read More

Original Article

Hydrogen Sulfide Solubility in Aqueous Solutions of MDEA, MEA, and DEA: Bridging Theory and Experiment with eCPA Equation of State

Fariborz Fazelipour; Shahin Alizadeh; Abolfazl Mohammadi; Alireza Bozorgian

Articles in Press, Accepted Manuscript, Available Online from 24 November 2023

https://doi.org/10.48309/chemm.2023.419075.1734

Abstract

Gas treatment procedures play a crucial role in eliminating acidic gases from natural gas and other hydrocarbon streams. Within the confines of this investigation, we propose an innovative ... Read More

Original Article

A New and Safe Spirocyclic Alkoxy Phosphazene: Synthesis, Characterization, DFT, Molecular Docking and Photophysical Properties

Camelia Gholamrezazadeh; Mohammad Hakimi; Mehdi Dadmehr

Articles in Press, Accepted Manuscript, Available Online from 25 November 2023

https://doi.org/10.48309/chemm.2023.422145.1735

Abstract

An eight-membered spiro-alkoxy compound Tris[N-(2-(λ1-oxidanyl(ethyl)-2-(λ2-azanyl) ethan-1-amine] N3P3(OC2H5NC2H5N)3 was synthesized by replacing the chlorine atoms of ... Read More

Facts & Figures
Google Scholar (h-index)	25
Google Scholar (i10-index)	96
Google Scholar Citations	2659
WOS Citation	2240
Impact Factor 2022	5.6
h-index in WOS	43
Average citations per item	7.93
Quality Rank in JCR List (2022)	Q2
Journal Citation Indicator (JCI), (2022)	0.59
Issue per year	12
No. of volumes	7
No. of Issues	46
Number of Articles	379
Rejected papers	304
Acceptance rate	51
Review papers	11
Number of Submissions	739
No. of contributors	1,018
Time to Accept (Days)	62
Article view	374,707
PDF download	165,523
No. of reviewers	8294
Contributing countries	30
No. of databases	15

Volume 7 (2023)

Volume 6 (2022)

Volume 5 (2021)

Volume 4 (2020)

Volume 3 (2019)

Volume 2 (2018)

Volume 1 (2017)

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